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The ISF1-X incubator shaker is suitable for applications in modern laboratories, research centres and production facilities. It offers a large shaking capacity with a small footprint and also many features allowing straightforward, safe handling of product.
| Up to three machines can be stacked |
Large shaking capacity with small footprint
Adjustable shaking diameters
Heating and cooling
CO2 and controlled humidity options available
5 year warranty
Cooling
CO2 control
Humidity control
All ISF1-X components are designed for durability and reliability. A Kuhner shaker is a cost effective investment in quality backed with a five year warranty.
Up to three ISF1-X shaking incubators can be stacked together for greater shaking capacity. Stacking is a simple procedure without the need for special tools or stacking kits. Each machine operates independently and can be equipped with cooling if required. For cell cultivation the ISF1-X is available with CO2. If using microtiter plates or particularly long cultivation times in shake flasks, the controlled humidity option will help reduce evaporation.
The maintenance-free direct drive is both long lasting and economical. The drive is protected from spills and the all stainless steel interior has a drain at the back for quick removal of any unwanted liquids. The incubator chamber can be cleaned with chemicals or sterilized using optional UV lighting. Kuhner’s direct drive system allows the shaking diameter to be changed at any time as well as guaranteeing low energy consumption.
An upward opening door fitted with a safety switch, means the ISF1-X is easy to load and unload. Automatic supervision of the mains voltage protects the shaker and in the event of a voltage spike the unit disconnects from the mains. The machine resumes operation at the set values once power is restored.
The ISF1-X sets today’s standard for incubator shakers thanks to its technology and functionality. To keep it that way, Kuhner maintains close contact with well-known universities and experts. We constantly investigate new developments looking for opportunities to further optimise the design and performance of our machines.
SMX1501 | SMX1503 | |
SMX1501C* | SMX1503C* | |
Cooling | yes | yes |
Humidity control | no | yes |
Temperature minimum | ambient - 15°C (- 10°C)* | ambient - 15°C (- 10°C)* |
Temperature maximum | 80°C (60°C)* | 80°C (60°C)* |
Humidity maximum | - | 85 % r.h. |
Power consumption | < 1500W | < 2000W |
* incubator shaker optimised for cell cultivation Technical data subject to change | ||
Gas volume | 395 l |
Weight (with cooling) | 210 kg |
Illumination | LED |
Operation menu in | German, French, English, Italian, Spanish |
Interface, standard | CAN-Bus |
Interface, optional | USB, Ethernet, digital, analogue |
Ambient temperature | 10°C up to 35°C |
Left sidewall
Cable feedthrough: PG 16 (ID 20mm)
Optional: 2nd cable feedthrough
Setting, digital | 0.1°C |
Accuracy, absolute | ± 0.30°C (37°C) ± 0.25°C (37°C)* |
Principle of sensor | Pt-100 |
Power of heating | 1000W |
Power of cooling (electric) | 125…270W |
Air circulation | 300m3/h |
(SMX1503) | |
max. at 25..55°C | 85% r.h. |
Setting, digital | 1% r.h. |
Accuracy, absolute | ± 2% r.h. |
Principle of sensor | capacitive |
Water refill | automatic |
Water heater | 300W |
Door heater | 100W |
(SMX1034) | |
Principle of sensor | Infrared, NDIR |
Measuring range | 0...20% CO2 |
Setting, digital | 0.1% |
Accuracy, absolute | ± 0.40% at 5% CO2 |
| 5...60°C |
CO2-supply | max. 2 bar overpressure |
SMX1021: | 220 - 240 V / 50-60 Hz |
SMX1022: | 190 - 210 V / 50-60 Hz |
SMX1023: | 110 - 120 V / 50-60 Hz |
SMX1024: | 95 - 105 V / 50-60 Hz |
Tray, size | F (800x420mm) |
Loading, maximum | 25kg |
Setting, digital | 1rpm |
Accuracy, absolute | ± 0.5 rpm |
Timer | 1s ... 999h |
Acceleration | controlled |
Active brake | adjustable |
Stop on position | adjustable |
Speed | |
* orbital, Ø 12.5mm | 20...500 rpm |
* orbital, Ø 25.0mm | 20...400 rpm |
* orbital, Ø 50.0mm | 20...300 rpm |
* linear, ↔ 12.5mm | 20...400 rpm |
* linear, ↔ 25.0mm | 20...300 rpm |
* linear, ↔ 50.0 mm | 20…200 rpm |
* can be changed | |
Technical data subject to change
Touchscreen with Kuhner Insight Software for simple operation, monitoring and programming of incubator shakers.
Have you heard about our new EcoDew®-Technology? Find more information under kuhner technology.
New:
Automatic door option
for ISF1-X
EPFL-table for 50ml bioreactors
CO2 control is essential when working with mammalian cell cultures. Kuhner was the first company to manufacture and supply incubator shakers with CO2 control more than 15 years ago and continues to offer this option. More.
All
Kuhner incubator shakers can be fitted with cooling. The refrigeration system
is regulated by a fully digital PID control ensuring minimal energy
consumption. The cooling is switched on only when required as determined by the
chamber temperature and set point. More.
Humidity control is an important factor in successful fermentation. Evaporation from microtiter plates, or when cultivating in flasks for long periods (e.g. cell cultures), can be significantly reduced with humidification.
To reduce evaporation from shake flasks or microtiter plates a water bath is placed inside the incubator. This water bath is fitted with an automatic water supply.
Our newly developed EcoDew®-Technology provides precise humidity control. More.
The ceiling of any Kuhner incubator shaker can be fitted with LED modules for the cultivation of phototrophic organisms. The control module allows full programming of night/day cycles and variable light intensity.
As in a biological safety cabinet, the chamber of a Kuhner incubator shaker can also be sterilized with an integrated UV lamp. The lamp is situated to maximise irradiation of the chamber and shaking table. The UV lamp has a clearly marked external switch and when the door is opened, the UV-lighting is automatically switched off.
Kuhner has designed a new light shade plate for the ISF1-X. This plate is easily placed in front of the door window to prevent radiation affecting the contents of the incubator chamber. It protects light sensitive media from UV, artificial and/or daylight.
Simply lift up the light shade plate to look at the cultures without opening the incubator door. When light protection is no longer required, the plate is easily removed.
Check out the Kuhner EquipNote "Light protection for Kuhner incubators".
Available for light sensitive medium or organisms. Any Kuhner incubator shaker can be delivered with blackened windows to prevent unwanted daylight or UV radiation inside the incubator.
Check out the Kuhner EquipNote "Light protection for Kuhner incubators".
The
ISF1-X incubator shaker with automatic door is designed for easy handling and maximum
comfort. The automatic door is activated by pressing a button on the incubator
shaker. A foot switch option is also available.
Labelling plates are now available for the ISF1-X foot switch that is used with the automatic door option. For a stack of 2x or 3x ISF1-X incubator shakers with the automatic door feature, these labelling plates will allow the user to easily identify which foot pedal corresponds to each machine.
This option includes a 9-inch touchscreen with our Kuhner Insight Software. The touchscreen has been designed for simple operation, monitoring and programming. It can also be retrofitted to existing incubator shakers. More.
The pull-out table is designed for the ISF1-X and ISF4-X incubator shakers as well as the Rack System. This remarkable device makes loading and unloading trays much easier.
The dual table is an easy and economical way of doubling the shaking capacity. The dual shaking table consists of two levels. Each level will accept an F size tray. However, with the dual table the shaking speed is limited to a maximum of 200 rpm.
Are you screening using large numbers of 50ml bioreactors (TPP, Falcon tubes etc.)? Then our new EPFL-table is the ideal solution. This table accepts up to five tube holders, each with a capacity of 24 x 50ml tubes. Each tube holder has its own clamp handle allowing it to be easily taken out of the incubator shaker and put on a clean bench while the other tubes keep on shaking. It’s also possible to shake microtiter plates on the EPFL-table, using Duetz 4-place coverclamps. If you have a Kuhner F-size tray (800 x 420mm), you can also clamp that on the table instead of individual holders. The TabCom Option is not possible with an EPFL-table. The TabCom Option is not possible with an EPFL-table.
An EPFL-table with 4 clamp positions is also available for the ES-X Lab-Shaker.
EPFL-table
EPFL-table with different holders
F-size tray clamped on the EPFL-table
Clamp handle
The outside
surface of the ISF1-X is completely made of stainless steel. The design of the
ISF1-X incubator shaker is optimized for the work in cleanrooms and GMP
environments (21 CFR Part 11). Interface and software also comply with GMP
regulations (GAMP5 Category 4).
Kuhner TOM (Transfer-Rate Online
Measurement) measures online oxygen transfer rate (OTR), carbon dioxide
transfer rate (CTR) and the respiratory quotient (RQ) in up to 16 individual
shake flasks for better process understanding and informed process development.
TOM is easily installed in any Kuhner shaker and can be operated with various
flask types and sizes including single use shake flasks. Kuhner TOM has zero
footprint on the shaker tray as it is mounted above (see picture below). More.
To prevent accidental operation of the controllers, the panel can be protected by a perspex cover.
The TabCom option from Kuhner consists of a cable for power and data with the connection port integrated in the shaking table (see pictures below). A cable guide prevents the cable breaking and ensures secure data recording. The flexibility of TabCom means online measurement systems can be easily integrated.
IQ-OQ (Installation Qualification and Operation Qualification) is an equipment qualification according to GMP procedure. Kuhner offers this service which can also be carried out at the customer’s premises.
Need more space in your laboratory? Check out our stacking adapter or universal stacking adapter.
The universal tray can be fitted with clamps for Erlenmeyer flasks, test tube holders, microtiter plates, or custom made holders to suit your requirements. Rearranging these clamps and holders is quick and simple.
Order number | Description |
|---|---|
SM3003 | Universal tray FU (800 x 420 mm) |
SM312500U | Clamp U-2500 for Ultra Yield flask from Thomson |
FU-tray with 8x Ultra Yield flasks (2500 mL) from Thomson
A special F-size universal tray (800x420mm) is now available to shake large Erlenmeyer flasks. It is ideal for cell culture.
This tray allows parallel shaking of 7 x 3L Corning Fernbach culture flasks or 7 x 5L Thomson Optimum Growth flasks at a maximum orbital diameter of 50mm. The FUM-V has no handles and a V support underneath the tray raises it above the clamping mechanism creating more space for flasks.
Clamps must be ordered separately. (Order number: SM313000F)
Order number | Description |
|---|---|
SMX310001 | Special universal tray, FUM-V with V support |
SM313000F | U-3000F clamp for Fernbach flasks: |
The
clamps are riveted onto this tray and cannot be removed. It offers
maximum stability and will often hold a larger number of flasks than an
universal
tray.
Ordner number | Description | Number of clamps |
|---|---|---|
SM330025 | F-25 ml | 153 |
SM330050 | F-50 ml | 100 |
SM330100 | F-100 ml | 74 |
SM330125 | F-125 ml | 60 |
SM330150 | F-150 ml | 60 |
SM330200 | F-200 ml | 40 |
SM330250 | F-250 ml | 40 |
SM330300 | F-300 ml | 30 |
SM330500 | F-500 ml | 26 |
SM331000 | F-1000 ml | 16 |
SM331500 | F-1500 ml | 12 |
SM332000 | F-2000 ml | 9 |
SM332500U | F-2500U | 8 |
SM333000 | F-3000 ml | 8 |
SM334000 | F-4000 ml | 5 |
SM335000 | F-5000 ml | 4 |
Kuhner has designed trays specifically for microtiter plates. Handles at the front of the tray open and close the special clamping mechanism allowing plates to be loaded and unloaded. Trays of different heights (22, 47 and 77mm) allow the stacking of up to four microtiter plates. The trays are available in three sizes and suitable for all types of plates (deep well, low well, 24, 48 and 96 well).
Order number | Description | Number of microtiter plates |
|---|---|---|
SM3503.22 | F-MT.22 | 24 - 48 |
SM3503.47 | F-MT.47 | 24 - 96 |
SM3503.77 | F-MT.77 | 24 - 144 |
Kuhner has designed a new tray for microtiter plates. This tray is fitted with springs which allows each well plate to be loaded and unloaded individually. The tray is available in three sizes: E (420x420mm), EX (500x420mm) and F (800x420mm).
This new tray is particularly suitable for the special holder with filter lid for deep well microtiter plates.
Order number | Description | Number of microtiter plates |
|---|---|---|
SM3503A | F-tray (800x420mm) for deepwell or microtiter plates | 1-24 |
F-tray (800 x 420 mm)
Kuhner has designed a new F-size tray (800 x 420mm) which is ideal for cell culture. The F-V5000/7 tray allows parallel shaking of 7 x 3L Corning Fernbach culture flasks, 7 x 5L Corning Erlenmeyer flasks or 7 x 5L Thomson Optimum Growth flasks. Flasks are held in position by pins and are easily placed on the tray and removed just as quickly.
This tray has been designed for easy cleaning and efficient handling of samples.
Order number | Description |
|---|---|
SM335000S |
F-V5000/7 |
The whole tray is covered with a rubber mat and is particularly suitable for shaking containers at low speed (e.g. blood bags).
Order number | Description |
|---|---|
SM3603 | Rubber mat FG (800 x 420 mm) |
A tray fitted with sticky strips is especially useful for flasks shaken at low speeds (up to 200rpm). The flask is placed directly on the sticky strip without the need for any other support. Flasks of all sizes can be used. Sticky strips are available individually or in sets and can also be supplied already fitted to a tray. The E-size tray accepts four strips, while the EX-size tray requires five strips and the F-size tray eight strips.
Ordner number | Description |
|---|---|
SMX350001K | F-size
tray with 8 sticky strips (clear) |
SMX837001K | 1
sticky strip: 385 x 85 x 3 mm (clear) |
The PC-plate increases the adhesion of the sticky strips. This is particularly helpful if using flasks >500ml.
Order number | Description |
|---|---|
SMX350007K | F-size tray with 8 sticky strips (clear) |
SMX350005K | F-size tray with 2 big sticky strips (clear) |
SMX837001K | 1 sticky strip: 385 x 85 x 3mm (clear) |
SMX837002K | 1 big sticky strip: 395 x 385 x 3mm (clear) |
The
dual tray offers two shaking levels and doubles the capacity. It is available
in EXU, EX, FU and F size and the upper tray can be removed.
Please note the shaking speed is limited.
Order number | Description |
|---|---|
SMX3015 | two FU trays with 180mm distance (with holes) |
SMX3016 |
two F trays with 180mm distance |
SMX3017 | two FU trays with 200mm distance (with holes) |
SMX3018 |
two F trays with 200mm distance |
This tray offers an alternative to both clamps and sticky mats and is ideal for tall containers. The tray is covered with a rubber mat and has an upright at each corner. The F-tray is fitted with six cross supports. These support bars securely clamp containers.
Order number | Description | Number of longitudinal girders |
|---|---|---|
SM4130.6 | FA-tray
with rubber mat and 6 cross supports | 2 |
Kuhner has also designed a special tray for shaking separating vessels. This very flexible tray can take vessels of various sizes. It is also possible to add a second layer and double the capacity. Movable retaining rods allow vessels to be installed easily.
Order number | Description | Number of separating vessels |
|---|---|---|
SM430250 | FS-250 | 10 |
SM4302502 | FS-250/2 | 20 (2 layers) |
SM430500 | FS-500 | 8 |
SM4305002 | FS-500/2 | 16 (2 layers) |
SM431000 | FS-1000 | 6 |
SM4310002 | FS-1000/2 | 12 (2 layers) |
This tray was developed to shake (orbital or linear) 2D-Bags. Rubber bands secure for example smaller blood and cryo bags. The tray is compatible with ISF1-X, ISF4-X, Rack System (SBM/SS-X), LS-X and ES-X shakers. It accepts various brands and sizes of pillow shaped single-use bags:
| Order number | Description |
|---|---|
SMX350301 | F-tray for 2D-bag with working volume 1/5/10L |
This tray was developed for shaking (orbital or linear) different types of 2D-bag. The tray consists of an aluminium base with a flexible mounting system on top.The mounting system can be manually adjusted to facilitate the controlled fixing of different sized cultivation bags. The mounting bars on both longitudinal sides can be moved up and down to hold the cultivation bag in place, while rubber bands will secure the smaller blood and cryo bags. The F-2D-Bag-tray is compatible with ISF1-X, ISF4-X, Rack System (SBM/SS-X), LS-X and ES-X shakers. The tray accepts various brands and sizes of pillow shaped single-use bags:
Visit our poster gallery and find more information on the poster "Characterisation of a RSB 20 L.pdf"
| Order number | Description |
|---|---|
SMX350302 | F-Tray for 2D-bag
with working volume 1/5/10L |
For a comfortable working height Kuhner offers floor stands for both the ISF1-X and LT-X incubator shakers. These are available in a choice of 400mm or 765mm high.
Order number | Description |
|---|---|
SM1560 | 400
mm high for 2 x ISF1-X |
SM1561 | 765
mm high for 1 x ISF1-X |
Floor stands with wheels are available for both the ISF1-X and LT-X incubator shakers. These stands enable the user to move the machines easily. However, the shaking speed is limited.
Order number | Description |
|---|---|
SMX1560A | 400
mm high for 2 x ISF1-X |
SMX1561A | 765
mm high for 1 x ISF1-X |
SMX1040 | Upgrade costs for castors (Polyamid) |
*only
for new machines | |
The universal stacking adapter allows other equipment to be placed on top of an ISF1-X incubator shaker, providing an additional work surface. Create more space in your laboratory with the universal stacking adapter.
Ordner number | Description |
|---|---|
SMX1576 | Universal
stacking adapter on ISF1-X |
This stacking adapter is designed for stacking a LT-X on an ISF1-X incubator shaker. Extra work space on the adapter allows room for flasks or a small machine, as well as the LT-X, thus creating a greater working area.
Order number | Desciption |
|---|---|
SMX1575 | Stacking
adapter (LT-X on ISF1-X) |
The user-friendly Kuhner Insight software was developed for supervision, monitoring, and recording of data. The software is easy to operate. More.
Kuhner shakers are equipped with a CAN-bus. CAN-USB, CAN-Ethernet, EMI-60 and NET-60 are all well established interfaces. More.
The ISF1-X incubator shakers can be fitted with a shelf allowing cultivation in petri dishes. One or two shelves can be placed above the shaking table and fixed to the chamber walls with four screws.
Order number | Description |
|---|---|
SMX1572 | Shelf for ISF1-X |
To reduce evaporation from shake flasks or microtiter plates a Teflon coated water bath can be placed inside the incubator. This water bath is not fitted with an automatic water supply and must be topped up manually
Order number | Description |
|---|---|
SMX1533B | Humidity
bath, coated, for ISF1-X and ISF4-X |
Kuhner has designed a new light shade plate for the ISF1-X. This plate is easily placed in front of the door window to prevent radiation affecting the contents of the incubator chamber. It protects light sensitive media from UV, artificial and/or daylight.
Simply lift up the light shade plate to look at the cultures without opening the incubator door. When light protection is no longer required, the plate is easily removed.
Check out the Kuhner EquipNote "Light protection for Kuhner incubators".
Order number | Description |
|---|---|
SMX1554 | Light shade plate for ISF1-X/Z |
Light protection for Kuhner incubators:
Characterisation of a RSB 20 L
Evaporation and Aeration in Shaken Bioreactors
Orbital Shaken Bioreactors
The Scale Up Fast Track
Characterisation of a RSB 20 L
Characterization of Algal Cell Culture in Photobioreactors
In our Science Room, we offer general information and data of cultivation processes in shaken bioreactors.
The ISF1-X incubator shaker with automatic door is designed for easy handling and maximum comfort. The automatic door is activated by pressing a button on the incubator shaker. A foot switch option is also available.
Check out our ISF1-X shaker running with 1000 rpm (3mm shaking diameter).
No, Kuhner machines do not need kits or special tools for stacking. Full instructions are provided in the User Manual.
Yes
Yes, but please make sure you stack the W-series shakers on top of the X-series and not vice versa.
Yes
Yes
The following flyers provide information about the machines and function-specific solutions.
Kuhner shakers are suitable for the cultivation of microbial, plant, human and animal cell cultures. Find more information about the different application areas and suitable product recommendations for optimal cultivation here.
Adolf Kühner AG (Headquarters)
Dinkelbergstrasse 1
CH-4127 Birsfelden (Basel)
Switzerland
We support our customers in implementation, maintenance and repair of all Kuhner products – efficiently and competently.
For Kuhner, the quality and durability of their shakers and bioreactors have always been the topics with the highest priority. On this account, Kuhner products have also proven their worth worldwide under GMP requirements. Documentation, development and production along the full life cycle of our products are continuously enhanced to match the requirements of 21 CFR and GAMP 5.
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The world's most reliable shaking machines built in-house in Switzerland.
