With the unique CHRIST micro balance you can monitor the progress in the drying process without any influences to the process. The transition from sublimation to desorption can be determined as well as the drying speed using different p,T-profiles. Thus the drying cycles can be optimized. You obtain stable products without the need of needlessley long drying cycles. Limitations: The high accuracy of measurement is limited to -40°C ... +40°C and the balance can't be used in sterile processes.

Figure 3:
Determination of end of main drying by using the micro balance  

Figure 4:
Effect of shelf temperature and vacuum to the sublimation rate measured
with the micro balance